Alloclae

Next-Generation PLLA Biostimulation for Gradual, Natural Collagen Restoration

Expertise

Top 1%
Injector in US

Experience

11+ Years
12k + Patients

Excellence

36+ Top lasers
25+ Injectables

Why Choose Dr. Avaliani for Alloclae?

Alloclae (AestheFill) is a next-generation poly-L-lactic acid (PLLA) biostimulator that gradually rebuilds your body’s own collagen for natural-looking volume restoration. Unlike traditional fillers that simply add volume, Alloclae stimulates your skin to regenerate its structural foundation from within — delivering results that develop naturally over weeks and last up to two years or more.

Biostimulator Specialist

Extensive experience with PLLA biostimulators including Alloclae (AestheFill) and Sculptra — Dr. Avaliani understands the precise injection techniques required for optimal collagen stimulation

Board-Certified Physician

11+ years of aesthetic medicine experience — every Alloclae treatment protocol is personally designed and performed by Dr. Avaliani for safe, predictable collagen restoration

Gradual, Natural Results

Results develop gradually over weeks and months as your body produces new collagen — no one will know you had a treatment, just that you look refreshed and rejuvenated

A Reputation Built on Results

5.0-star rating with 565+ verified patient reviews and proven collagen restoration outcomes with biostimulator treatments

Personalized Approach

Customized biostimulator protocols tailored to your specific volume loss patterns, facial anatomy, and long-term rejuvenation goals

What Is Alloclae?

Alloclae (also known as AestheFill) is a poly-L-lactic acid (PLLA) biostimulator injectable that works by stimulating your body’s own collagen production. Rather than simply filling in volume like traditional hyaluronic acid fillers, Alloclae triggers a natural regenerative process that gradually rebuilds the structural collagen framework beneath your skin — restoring volume, firmness, and youthful contour over time.

At Dr. Avaliani’s practice, every Alloclae session is performed with meticulous precision. The PLLA microspheres are injected strategically into areas of volume loss using advanced technique. Once placed, the microspheres act as a scaffold that stimulates fibroblasts to produce new collagen, gradually restoring the fullness and structure that aging has diminished.

How Alloclae Biostimulation Works

The Alloclae biostimulation protocol follows a carefully designed process:

Dr. Avaliani performs a comprehensive facial assessment to map areas of volume loss and collagen depletion

Alloclae is reconstituted and precisely injected into the targeted areas using a specialized technique

The PLLA microspheres create a scaffold that stimulates your fibroblasts to produce new collagen

Over the following weeks and months, new collagen gradually forms, restoring natural volume and firmness

A series of 2–3 treatments spaced 4–6 weeks apart builds progressive, long-lasting collagen restoration

Concerns We Treat with Alloclae

Facial Volume Loss

Generalized facial volume depletion from aging, weight loss, or collagen breakdown. Alloclae gradually rebuilds the underlying collagen structure, restoring a fuller, more youthful facial appearance without the overfilled look of traditional fillers.

Temple Hollowing

Sunken, hollow temples that create an aged, gaunt appearance and disrupt facial harmony. Alloclae biostimulation gradually fills the temporal fossa by stimulating collagen production in the deep tissue, restoring smooth, natural contour.

Cheek Deflation

Loss of cheek volume that causes the midface to flatten and sag, creating a tired or aged look. Alloclae restores the cheek mounds’ underlying structural support through gradual collagen regeneration for natural lift.

Jawline Definition

Softened or undefined jawline caused by collagen loss and skin laxity along the lower face. Alloclae rebuilds the collagen foundation along the jawline, restoring definition and a more sculpted profile over time.

Hand Rejuvenation

Thin, bony-looking hands with visible tendons and veins caused by volume and collagen loss. Alloclae stimulates new collagen in the dorsal hand area, gradually restoring plumpness and a more youthful hand appearance.

Collagen Depletion

Overall collagen breakdown from aging, sun damage, or lifestyle factors that leads to skin thinning, fine lines, and loss of structural support. Alloclae addresses the root cause by stimulating your body to produce new, healthy collagen.

Our Alloclae Treatment Options

Dr. Avaliani offers a comprehensive biostimulator approach for optimal collagen restoration. Here’s how Alloclae fits into her treatment portfolio:

Alloclae (PLLA Biostimulator)
A next-generation poly-L-lactic acid biostimulator that stimulates your body’s own collagen production for gradual, natural volume restoration. Results develop over weeks and last up to 2+ years. Ideal for temples, cheeks, jawline, and hands.
Complementary: Sculptra®
Another PLLA-based biostimulator with a long track record of safety and efficacy. Dr. Avaliani may recommend Sculptra as an alternative or complement to Alloclae depending on your specific anatomy and treatment goals. Both stimulate collagen production for long-lasting results.
Biostimulator Combination Protocol
Dr. Avaliani may combine Alloclae with dermal fillers, skin boosters, or other treatments for comprehensive facial rejuvenation. Biostimulators rebuild the deep collagen foundation while complementary treatments address surface texture, hydration, and immediate volume needs.

Does It Hurt?

Your Comfort Options (We Tailor This to You)

Alloclae treatment is well tolerated by most patients. Topical numbing cream is applied before the procedure, and lidocaine is mixed directly with the Alloclae product to minimize discomfort during injection. Most patients describe a mild pressure or slight stinging sensation that subsides quickly. Any injection-site swelling typically resolves within 2–5 days.

Dr. Avaliani prioritizes your comfort at every step. A post-treatment massage protocol is performed to distribute the product evenly and ensure optimal collagen stimulation. You will also be instructed to self-massage the treated areas for several days following the procedure. Pro-Nox (nitrous oxide) is available for patients who prefer additional relaxation during treatment.

Feel Calm. Stay in Control. Look Amazing.

Reduced Anxiety

Settle into a calm, relaxed state before and during your treatment — no stress, no tension.

Less Discomfort

Enhanced comfort for your treatment, so you can focus on your results.

No Downtime

Walk out feeling great and drive yourself home — absolutely no recovery time required.

PRO-NOX

Nitrous Oxide

Available On Request

For patients who prefer an extra layer of relaxation, Pro‑Nox™ provides a gentle, calming effect that wears off instantly. Most patients find their treatments very manageable — but it’s always here if you want it.

View Before &
After Gallery

Is Alloclae Right for Me?

Ideal Candidates

You may be a good candidate if you:

Are experiencing facial volume loss from aging, collagen depletion, or weight loss

Want gradual, natural-looking results rather than immediate filler volume

Are looking for long-lasting collagen restoration that improves over time

Have hollowing in the temples, cheeks, jawline, or backs of hands

Are in good overall health and willing to commit to a series of 2–3 treatment sessions

Want a biostimulator alternative to traditional fillers for a more natural rejuvenation approach

What Does Alloclae Cost?

Pricing Information

The cost of Alloclae treatment depends on the number of vials needed, the treatment areas, and the total number of sessions in your protocol.

Price Range:
Typically 2–3 sessions spaced 4–6 weeks apart for optimal collagen stimulation

During your consultation, Dr. Avaliani will assess your collagen loss, map your areas of volume depletion, and recommend a customized Alloclae treatment protocol with transparent pricing. Results develop gradually and last up to 2+ years, making Alloclae an excellent long-term investment in your appearance.

*Medical Disclaimer
Individual results may vary. No guarantee of specific results can be given. The degree of side effects and duration of results may vary. Content is for informational
purposes and does not substitute for professional medical advice provided during an in-office consultation and examination by a physician.

Luxury Treatments.
Flexible Payment Options.

Your Confidence Should Never Have to Wait.

At Anna Avaliani MD Cosmetic & Laser Surgery, we believe exceptional aesthetic care should be accessible when you are ready — not months or years later. That’s why we offer elegant financing solutions that allow you to begin your transformation today while comfortably managing the investment over time. Because confidence is priceless — and now it’s flexible.

Alloclae Frequently Asked Questions

Follow Us

@dr.annaavaliani
Scroll to Top