Renuva®

The Allograft Adipose Matrix That Replaces Lost Volume with Your Own Fat Cells

Expertise

Top 1%
Injector in US

Experience

11+ Years
12k + Patients

Excellence

36+ Top lasers
25+ Injectables

Why Choose Dr. Avaliani for Renuva®?

Renuva® is the first off-the-shelf allograft adipose matrix designed to replenish age-related volume loss. Unlike traditional fillers, Renuva creates a honeycomb-type matrix that fills with your body’s own fat cells over 3–6 months, leaving your own biological tissue exactly where you need it. Manufactured by MTF Biologics, a nonprofit organization established in 1987, Renuva can potentially last up to 10 years as true biological tissue replacement.

Fat Matrix Technology

Renuva’s allograft adipose matrix creates a scaffold that your body fills with its own fat cells — the volume you gain is biologically yours, not a synthetic material, with potential longevity of up to 10 years

Board-Certified Physician

11+ years of aesthetic medicine experience — Dr. Avaliani personally performs every Renuva treatment using cannula technique for both facial and body applications

Biological Integration

Your body replaces the matrix with its own fat cells over 3–6 months — the result is true biological tissue, not a filler that dissolves, with potential longevity far exceeding traditional injectables

A Reputation Built on Results

5.0-star rating with 565+ verified patient reviews and proven biological volume restoration for face and body

Personalized Approach

Customized Renuva protocols for face, hands, body contouring, and correction of post-surgical irregularities

What Is Renuva®?

Renuva® is the first off-the-shelf allograft adipose matrix for volume restoration. Manufactured by MTF Biologics (est. 1987) using rigorous donor screening and advanced tissue processing, Renuva creates a honeycomb-type scaffold at the injection site. Over 3–6 months, your body fills this matrix with its own fat cells, resulting in true biological tissue replacement that can potentially last up to 10 years.

At Dr. Avaliani’s practice, every Renuva treatment is performed with meticulous precision using cannula technique for enhanced comfort and safety. Renuva can be used on both the face and body, treating areas that traditional fillers cannot effectively address. The procedure involves minimal downtime — typically just a few hours of swelling and tenderness. Most patients require 1–3 sessions for their desired correction.

How Renuva® Works

Renuva treatment follows a biological volume-restoration protocol:

Dr. Avaliani evaluates your volume loss areas and designs a treatment plan, determining the optimal amount of Renuva needed

The allograft adipose matrix is precisely injected using cannula technique into areas of volume loss on the face or body

Renuva creates a honeycomb-type scaffold that signals your body to recruit and deposit its own fat cells at the injection site

Over 3–6 months, the matrix remodels and is replaced by your own adipose tissue, creating true biological volume

The result is your own fat cells exactly where desired, with potential longevity of up to 10 years as natural tissue

Areas We Treat with Renuva®

Facial Volume Loss

Age-related volume depletion in the temples, cheeks, jawline, and smile lines. Renuva replaces lost volume with your own fat cells for biological restoration that lasts far longer than traditional fillers.

Hand Rejuvenation

Volume loss on the backs of the hands revealing tendons, veins, and bony structures. Renuva restores natural fat volume to the hands with biological tissue that integrates permanently into your anatomy.

Hip Dips

Indentations between the hip bone and upper thigh that create an uneven body silhouette. Renuva fills hip dips with biological tissue that becomes your own fat, creating smooth, natural curves without surgery.

Post-Surgical Irregularities

Contour deformities, dents, or irregularities left after liposuction or other surgical procedures. Renuva fills these defects with biological tissue that integrates naturally, smoothing uneven results.

Body Contouring

Volume enhancement for the buttocks, chest, abdomen, knees, and elbows. Renuva provides biological volume restoration for body areas where traditional fillers fall short or dissolve too quickly.

Neck & Décolletage

Volume loss and skin thinning in the neck and chest area that reveals aging. Renuva restores biological volume to these delicate areas where long-lasting correction is essential for natural-looking rejuvenation.

Renuva® Details

What makes Renuva® unique among injectable treatments:

Adipose Matrix Science
Renuva’s allograft adipose matrix creates a biological scaffold that signals your body to recruit and deposit its own fat cells. Over 3–6 months, the matrix remodels completely, leaving true adipose tissue that is biologically yours. This is not a filler — it is biological tissue replacement.
Exceptional Longevity
Because Renuva results in your own biological fat tissue, the volume can potentially last up to 10 years — dramatically exceeding HA fillers (6–18 months), Sculptra (2–4 years), and even RADIESSE (1–2 years). Most patients need just 1–3 treatment sessions for their desired correction.
Face & Body Versatility
Renuva treats both face and body — temples, cheeks, jawline, hands, hip dips, buttocks, chest, knees, elbows, and post-surgical irregularities. Dr. Avaliani uses cannula technique for enhanced comfort. Note: Renuva cannot be injected into muscle, tear troughs, nose, lips, or glabella.

Does It Hurt?

Your Comfort Options (We Tailor This to You)

Renuva treatment is very comfortable. Dr. Avaliani uses cannula technique for enhanced comfort and safety. The procedure involves minimal discomfort. Pro-Nox (nitrous oxide) is available upon request for additional relaxation. Most patients describe the sensation as mild pressure.

Downtime is minimal — typically just a few hours of swelling and tenderness. Return to normal activities the same day. Results develop gradually over 3–6 months as your body fills the matrix with its own fat cells. Most patients need 1–3 sessions. The biological tissue can potentially last up to 10 years.

Feel Calm. Stay in Control. Look Amazing.

Reduced Anxiety

Settle into a calm, relaxed state before and during your treatment — no stress, no tension.

Less Discomfort

Enhanced comfort for your treatment, so you can focus on your results.

No Downtime

Walk out feeling great and drive yourself home — absolutely no recovery time required.

PRO-NOX

Nitrous Oxide

Available On Request

For patients who prefer an extra layer of relaxation, Pro‑Nox™ provides a gentle, calming effect that wears off instantly. Most patients find their treatments very manageable — but it’s always here if you want it.

View Before &
After Gallery

Is Renuva® Right for Me?

Ideal Candidates

You may be a good candidate if you:

Have age-related volume loss in the face or body that you want corrected with biological tissue

Want results that last far longer than traditional fillers — potentially up to 10 years

Have post-surgical irregularities, hip dips, or contour deficiencies to correct

Want your own fat cells replacing lost volume rather than a synthetic filler

Have good skin quality and are willing to wait 3–6 months for full biological integration

Want biological tissue replacement for face, hands, or body areas where traditional fillers fall short

What Does Renuva® Cost?

Pricing Information

Renuva pricing reflects its superior regenerative properties and exceptional longevity compared to traditional fillers.

Price Range:
Results can potentially last up to 10 years, making Renuva one of the most cost-effective long-term volume solutions

During your consultation, Dr. Avaliani will evaluate your volume loss, skin quality, medical history, and goals to determine whether Renuva is ideal. Most patients need 1–3 sessions for their desired correction.

*Medical Disclaimer
Individual results may vary. No guarantee of specific results can be given. The degree of side effects and duration of results may vary. Content is for informational
purposes and does not substitute for professional medical advice provided during an in-office consultation and examination by a physician.

Luxury Treatments.
Flexible Payment Options.

Your Confidence Should Never Have to Wait.

At Anna Avaliani MD Cosmetic & Laser Surgery, we believe exceptional aesthetic care should be accessible when you are ready — not months or years later. That’s why we offer elegant financing solutions that allow you to begin your transformation today while comfortably managing the investment over time. Because confidence is priceless — and now it’s flexible.

Renuva® Frequently Asked Questions

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